(9aS)-octahydro-1H-Pyrrolo[1,2-a][1,4]diazepin-1-one synthesis

2synthesis methods

Product Name:(9aS)-octahydro-1H-Pyrrolo[1,2-a][1,4]diazepin-1-one
CAS Number:929048-31-7
Molecular formula:C8H14N2O
Molecular Weight:154.2096

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(9aS)-octahydro-1H-Pyrrolo[1,2-a][1,4]diazepin-1-one

929048-31-7
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: potassium hydroxide / water / 2.5 h / 50 - 70 °C
2: hydrogen / methanol; water / 6 h / 80 °C / 36003.6 Torr

References:

Bréthous, Lise;Garcia-Delgado, Noemi;Schwartz, Julian;Bertrand, Sonia;Bertrand, Daniel;Reymond, Jean-Louis [Journal of Medicinal Chemistry,2012,vol. 55,# 10,p. 4605 - 4618]

L-Proline, 1-(2-cyanoethyl)-, ethyl ester

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929048-31-7
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References