Cyclobutanol, 3-(8-aMino-1-broMoiMidazo[1,5-a]pyrazin-3-yl)-1-Methyl-, cis- synthesis

2synthesis methods

Product Name:Cyclobutanol, 3-(8-aMino-1-broMoiMidazo[1,5-a]pyrazin-3-yl)-1-Methyl-, cis-
CAS Number:936901-75-6
Molecular formula:C11H13BrN4O
Molecular Weight:297.15

(1s,3s)-3-(8-broMo-1-chloroH-pyrrolo[1,2-a]pyrazin-6-yl)-1-Methylcyclobutanol

936901-74-5
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Cyclobutanol, 3-(8-aMino-1-broMoiMidazo[1,5-a]pyrazin-3-yl)-1-Methyl-, cis-

936901-75-6
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Yield:936901-75-6 95%

Reaction Conditions:

with ammonium hydroxide in iso-butanol at 90;

References:

Jin, Meizhong;Wang, Jing;Kleinberg, Andrew;Kadalbajoo, Mridula;Siu, Kam W.;Cooke, Andrew;Bittner, Mark A.;Yao, Yan;Thelemann, April;Ji, Qunsheng;Bhagwat, Shripad;Mulvihill, Kristen M.;Rechka, Josef A.;Pachter, Jonathan A.;Crew, Andrew P.;Epstein, David;Mulvihill, Mark J. [Bioorganic and Medicinal Chemistry Letters,2013,vol. 23,# 4,p. 979 - 984]

936901-73-4 Synthesis

3-(8-broMo-1-chloroH-pyrrolo[1,2-a]pyrazin-6-yl)cyclobutanone

936901-73-4
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$405.60/250mg

936901-75-6
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References