4-[7-(4-carbamimidoylphenoxy)heptoxy]benzenecarboximidamide synthesis
- Product Name:4-[7-(4-carbamimidoylphenoxy)heptoxy]benzenecarboximidamide
- CAS Number:94345-47-8
- Molecular formula:C21H28N4O2
- Molecular Weight:368.47
224054-32-4
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Yield:94345-47-8 86%
Reaction Conditions:
Stage #1: 4,4′-(heptane-1,7-diylbis(oxy))dibenzonitrilewith lithium hexamethyldisilazane in tetrahydrofuran at 20;Inert atmosphere;
Stage #2: with hydrogenchloride in tetrahydrofuran at 0 - 20;
References:
Wesseling, Charlotte M. J.;Slingerland, Cornelis J.;Veraar, Shanice;Lok, Samantha;Martin, Nathaniel I. [ACS Infectious Diseases,2021,vol. 7,# 12,p. 3314 - 3335]