7-(CHLOROMETHYL)-2-METHYL-5H-[1,3]THIAZOLO[3,2-A]PYRIMIDIN-5-ONE synthesis
- Product Name:7-(CHLOROMETHYL)-2-METHYL-5H-[1,3]THIAZOLO[3,2-A]PYRIMIDIN-5-ONE
- CAS Number:943656-55-1
- Molecular formula:C8H7ClN2OS
- Molecular Weight:214.67
7305-71-7
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638-07-3
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943656-55-1
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Yield:-
Reaction Conditions:
with polyphosphoric acid at 110; for 1 h;
References:
Volgraf, Matthew;Sellers, Benjamin D.;Jiang, Yu;Wu, Guosheng;Ly, Cuong Q.;Villemure, Elisia;Pastor, Richard M.;Yuen, Po-Wai;Lu, Aijun;Luo, Xifeng;Liu, Mingcui;Zhang, Shun;Sun, Liang;Fu, Yuhong;Lupardus, Patrick J.;Wallweber, Heidi J.A.;Liederer, Bianca M.;Deshmukh, Gauri;Plise, Emile;Tay, Suzanne;Reynen, Paul;Herrington, James;Gustafson, Amy;Liu, Yichin;Dirksen, Akim;Dietz, Matthias G. A.;Liu, Yanzhou;Wang, Tzu-Ming;Hanson, Jesse E.;Hackos, David;Scearce-Levie, Kimberly;Schwarz, Jacob B. [Journal of Medicinal Chemistry,2016,vol. 59,# 6,p. 2760 - 2779]