Ethyl (1S,2R)-2-aminocyclopentane-1-carboxylate hydrochloride synthesis

1synthesis methods

Product Name:Ethyl (1S,2R)-2-aminocyclopentane-1-carboxylate hydrochloride
CAS Number:945935-60-4
Molecular formula:C8H16ClNO2
Molecular Weight:193.67

Ethyl (1S,2R)-2-aminocyclopentanecarboxylate

197904-11-3
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$155.00/100mg

Ethyl (1S,2R)-2-aminocyclopentane-1-carboxylate hydrochloride

945935-60-4
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Yield:945935-60-4 66%

Reaction Conditions:

with hydrogenchloride in 1,4-dioxane;ethyl acetate at 0 - 23;

References:

Dragovich, Peter S.;Murphy, Douglas E.;Dao, Kimkim;Kim, Sun Hee;Li, Lian-Sheng;Ruebsam, Frank;Sun, Zhongxiang;Tran, Chinh V.;Xiang, Alan X.;Zhou, Yuefen [Tetrahedron Asymmetry,2008,vol. 19,# 24,p. 2796 - 2803] Location in patent:experimental part