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6-piperazin-1-ylimidazo[1,2-b]pyridazine hydrochloride synthesis

1synthesis methods
110-85-0 Synthesis
Piperazine

110-85-0
549 suppliers
$5.00/5G

6775-78-6 Synthesis
6-Chloroimidazo[2,1-f]pyridazine

6775-78-6
276 suppliers
$6.00/1g

6-piperazin-1-ylimidazo[1,2-b]pyridazine hydrochloride

946157-08-0
10 suppliers
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Yield:946157-08-0 35%

Reaction Conditions:

with N,N-dimethyl-formamide in methanol;

References:

Hurth, Konstanze;Enz, Albert;Floersheim, Philipp;Gentsch, Conrad;Hoyer, Daniel;Langenegger, Daniel;Neumann, Peter;Pfaeffli, Paul;Sorg, Dieter;Swoboda, Robert;Vassout, Annick;Troxler, Thomas [Bioorganic and Medicinal Chemistry Letters,2007,vol. 17,# 14,p. 3988 - 3991]