Ethyl 5-hydroxymethyl-3-methylisoxazole-4-carboxylate synthesis

6synthesis methods

Product Name:Ethyl 5-hydroxymethyl-3-methylisoxazole-4-carboxylate
CAS Number:95104-40-8
Molecular formula:C8H11NO4
Molecular Weight:185.18

3511-34-0 Synthesis

3-Furancarboxylic acid, 4,5-dihydro-2-methyl-4-oxo-, ethyl ester

3511-34-0
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Ethyl 5-hydroxymethyl-3-methylisoxazole-4-carboxylate

95104-40-8
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$90.00/50mg

Yield:95104-40-8 98%

Reaction Conditions:

with hydroxylamine hydrochloride;sodium acetate in ethanol; for 1.33333 h;Reflux;Inert atmosphere;

References:

Zhurakovskyi, Oleksandr;Türkmen, Yunus E.;L?ffler, Lorenz E.;Moorthie, Vijayalakshmi A.;Chen, C. Chun;Shaw, Michael A.;Crimmin, Mark R.;Ferrara, Marco;Ahmad, Mushtaq;Ostovar, Mehrnoosh;Matlock, Johnathan V.;Aggarwal, Varinder K. [Angewandte Chemie - International Edition,2018,vol. 57,# 5,p. 1346 - 1350][Angew. Chem.,2018,vol. 130,p. 1360 - 1364,5] Location in patent:supporting information