(E)-3-((Dimethylamino)methylene)dihydro-2H-pyran-4(3H)-one synthesis
- Product Name:(E)-3-((Dimethylamino)methylene)dihydro-2H-pyran-4(3H)-one
- CAS Number:95502-31-1
- Molecular formula:C8H13NO2
- Molecular Weight:155.19
29943-42-8
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$5.00/1g
4637-24-5
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$5.00/25g
95502-31-1
14 suppliers
$303.00/1g
Yield:95502-31-1 81%
Reaction Conditions:
in N,N-dimethyl-formamide at 110; for 3 h;
Steps:
27.1 3-((dimethylamino)methylene)tetrahydro-4H-pyran-4-one
The reaction mixture tetrahydropyrone 27a (0.4 g, 4.0 mmol),N,N-dimethylformamide dimethyl acetal (0.48 g, 4.0 mmol) and N,N-dimethylformamide (4 ml) were heated to 110 ° C for 3 hours. Cool to room temperature and remove the solvent under reduced pressure. To give the desired product 3-((dimethylamino)methylene)tetrahydro-4H-pyran-4-one 27a (0.5g, orange solid), yield: 81%.
References:
CN109956927,2019,A Location in patent:Paragraph 0313; 0314
29943-42-8
427 suppliers
$5.00/1g
95502-31-1
14 suppliers
$303.00/1g
95502-30-0
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124-40-3
503 suppliers
$18.00/100ml
95502-31-1
14 suppliers
$303.00/1g