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{4-[4-(Trifluoromethoxy)phenoxy]phenyl}boronic acid synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: n-butyllithium / tetrahydrofuran / -78 °C
2: hydrogenchloride / water / 20 °C

References:

Bueno, José M.;Manzano, Pilar;García, María C.;Chicharro, Jesús;Puente, Margarita;Lorenzo, Milagros;García, Adolfo;Ferrer, Santiago;Gómez, Rubén M.;Fraile, María T.;Lavandera, José L.;Fiandor, José M.;Vidal, Jaume;Herreros, Esperanza;Gargallo-Viola, Domingo [Bioorganic and Medicinal Chemistry Letters,2011,vol. 21,# 18,p. 5214 - 5218]