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2-Cyclohexen-1-ol, 3-methyl-6-(1-methylethenyl)-, (1R,6R)- synthesis

4synthesis methods
35901-76-9 Synthesis
5-Methyl-4-hexenoic acid methyl ester

35901-76-9
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2-Cyclohexen-1-ol, 3-methyl-6-(1-methylethenyl)-, (1R,6R)-

96555-02-1
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Yield:-

Steps:

Multi-step reaction with 3 steps
1.1: sodium carbonate / 0.42 h / 20 °C
1.2: CuSO4·H2O chiral phosphine d / 9 h / 100 °C
2.1: water; sodium hydroxide / 2 h / 110 °C
3.1: sodium tetrahydroborate / ethyl acetate / 3 h / 105 °C

References:

CN112573996, 2021, A