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ChemicalBook CAS DataBase List N-(1-Benzylpiperidin-4-yl)-2,2,2-trifluoroacetamide

N-(1-Benzylpiperidin-4-yl)-2,2,2-trifluoroacetamide synthesis

2synthesis methods
50541-93-0 Synthesis
4-Amino-1-benzylpiperidine

50541-93-0
365 suppliers
$6.00/5g

407-25-0 Synthesis
Trifluoroacetic anhydride

407-25-0
438 suppliers
$9.00/1g

-

Yield:97181-50-5 94%

Reaction Conditions:

with triethylamine in dichloromethane at 0; for 0.25 h;

References:

Mach;Leudtke;Unsworth;Boundy;Nowak;Scripko;Elder;Jackson;Hoffman;Evora;Rao;Molinoff;Childers;Ehrenkaufer [Journal of Medicinal Chemistry,1993,vol. 36,# 23,p. 3707 - 3720]