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9H-Fluorene, 9-(chloromethyl)- synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: LAH / diethyl ether / Heating
2: SOCl2 / CH2Cl2 / Ambient temperature

References:

Arlt, Michael;Boettcher, Henning;Riethmueller, Angelika;Schneider, Guenter;Bartoszyk, Gerd D.;Greiner, Hartmut;Seyfried, Christoph A. [Bioorganic and Medicinal Chemistry Letters,1998,vol. 8,# 15,p. 2033 - 2038]