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(+)-a-Aminomethyl-o-chlorobenzyl alcohol synthesis

2synthesis methods
Benzeneethanamine, 2-chloro-β-[(octahydro-7,8,8-trimethyl-4,7-methanobenzofuran-2-yl)oxy]-, [2R-[2α(S*),3aα,4α,7α,7aα]]- (9CI)

133163-15-2
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4,7-Methanobenzofuran, octahydro-2-methoxy-7,8,8-trimethyl-, [2S-(2α,3aα,4α,7α,7aα)]- (9CI)

81925-10-2
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(+)-a-Aminomethyl-o-chlorobenzyl alcohol

128704-85-8
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Yield:81925-10-2 91% ,128704-85-8 83%

Reaction Conditions:

with hydrogenchloride in methanol;

References:

Noe, C. R.;Knollmueller, M.;Gaertner, P.;Fleischhacker, W.;Katikarides, E. [Monatshefte fur Chemie,1995,vol. 126,# 4,p. 481 - 494]

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