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AC-DL-PHE(4-F)-OME synthesis

6synthesis methods
2-Propenoic acid, 2-(acetylamino)-3-(4-fluorophenyl)-, methyl ester,(2Z)-

151073-39-1
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AC-DL-PHE(4-F)-OME

87586-97-8
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Yield:87586-97-8 > 95 %Spectr.

Reaction Conditions:

with di(norbornadiene)rhodium(I) tetrafluoroborate;hydrogen;C24H32O8*F6P(1-)*C35H35N2P*H(1+) in dichloromethane at 20; under 3800.26 Torr; for 1 h;Autoclave;

References:

Fan, Qing-Hua;He, Yan-Mei;Luo, Yi-Er;Tang, Yu-Ping;Xiang, Jun-Feng [Angewandte Chemie - International Edition,2022,vol. 61,# 15,art. no. E202200638][Angew. Chem.,2022,vol. 134,# 15] Location in patent:supporting information