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ChemicalBook CAS DataBase List Acelarin

Acelarin synthesis

6synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1: potassium carbonate / water; 1,4-dioxane / 48 h / 25 - 30 °C
2: 1,4-dioxane / 90 h / 25 - 45 °C
3: tert-butylmagnesium chloride / tetrahydrofuran / 0.5 h / -5 - 30 °C / Inert atmosphere
4: trifluoroacetic acid / dichloromethane / -2 - 10 °C

References:

NUCANA BIOMED LIMITED;LAURUS LABS PRIVATE LTD;DAMMALAPATI, Venkata Lakshmi Narasimha Rao;KOTALA, Mani Bushan;MADHAVARAM, Shankar WO2016/12781, 2016, A1