![](/CAS/GIF/90561-76-5.gif)
AcetaMide, N-[(4-broMophenyl)Methyl]- synthesis
- Product Name:AcetaMide, N-[(4-broMophenyl)Methyl]-
- CAS Number:90561-76-5
- Molecular formula:C9H10BrNO
- Molecular Weight:228.09
![4-Bromobenzylamine hydrochloride](/CAS/GIF/26177-44-6.gif)
26177-44-6
178 suppliers
$6.00/1g
![Acetyl chloride](/CAS/GIF/75-36-5.gif)
75-36-5
563 suppliers
$17.92/100G
![AcetaMide, N-[(4-broMophenyl)Methyl]-](/CAS/GIF/90561-76-5.gif)
90561-76-5
25 suppliers
$45.00/25mg
Yield:90561-76-5 100%
Reaction Conditions:
with triethylamine in dichloromethane at 0 - 30; for 2 h;
Steps:
48.48a
Step 48a: N-(4-bromobenzyl)acetamide (Compound 0601-135)To the solution of 4-bromobenzylamine hydrochloride (1.2 g, 5.4 mmol) and Et3N (5.5 g, 54 mmol) in dichloromethane (10 mL) was added CH3COCl (555 mg, 7.02 mmol) at 0 °C and stirred for 2 hr at 30 °C. Then the mixture was concentrated and the residue was dissolved in CH2C12 (30 mL), washed with water, dried over Na2S04 and concentrated to obtain 0601-135 (1.3 g, 100%) as a yellow solid. LCMS: 228 [M+l]+, 1H NMR (400 MHz, OMSO-d6) δ 2.00 (s, 3H), 4.33 (d, J= 6.4 Hz, 2H), 6.26 (s, 1H), 7.13 (d, J= 8.4 Hz, 2H), 7.43 (d, J= 8.4 Hz, 2H).
References:
WO2011/130628,2011,A1 Location in patent:Page/Page column 183-184
![4-Bromotoluene](/CAS/GIF/106-38-7.gif)
106-38-7
392 suppliers
$14.00/5g
![Acetonitrile](/CAS/GIF/75-05-8.gif)
75-05-8
968 suppliers
$10.00/10g
![AcetaMide, N-[(4-broMophenyl)Methyl]-](/CAS/GIF/90561-76-5.gif)
90561-76-5
25 suppliers
$45.00/25mg
![4-Bromobenzylamine](/CAS/GIF/3959-07-7.gif)
3959-07-7
200 suppliers
$10.00/1g
![Acetic anhydride](/CAS/20180808/GIF/108-24-7.gif)
108-24-7
5 suppliers
$14.00/250ML
![AcetaMide, N-[(4-broMophenyl)Methyl]-](/CAS/GIF/90561-76-5.gif)
90561-76-5
25 suppliers
$45.00/25mg
![4-Bromobenzylamine](/CAS/GIF/3959-07-7.gif)
3959-07-7
200 suppliers
$10.00/1g
![Ethyl acetate](/CAS/GIF/141-78-6.gif)
141-78-6
607 suppliers
$22.37/250ml
![AcetaMide, N-[(4-broMophenyl)Methyl]-](/CAS/GIF/90561-76-5.gif)
90561-76-5
25 suppliers
$45.00/25mg
201230-82-2
1 suppliers
inquiry
![Dicumyl peroxide](/CAS/GIF/80-43-3.gif)
80-43-3
4 suppliers
$36.70/100g
![4-Bromobenzylamine](/CAS/GIF/3959-07-7.gif)
3959-07-7
200 suppliers
$10.00/1g
![AcetaMide, N-[(4-broMophenyl)Methyl]-](/CAS/GIF/90561-76-5.gif)
90561-76-5
25 suppliers
$45.00/25mg