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Acridine-4,9-dicarboxylic acid monohydrate synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 60 percent / CuI, Cu poeder, K2CO3 / dimethylsulfoxide / 1 h / 110 °C
2: 2 N aq. HCl / 4 h / Heating

References:

Spicer, Julie A.;Gamage, Swarna A.;Atwell, Graham J.;Finlay, Graeme J.;Baguley, Bruce C.;Denny, William A. [Journal of Medicinal Chemistry,1997,vol. 40,# 12,p. 1919 - 1929]

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