![](/CAS/GIF/6654-36-0.gif)
ADIPIC SEMIALDEHYDE METHYL ESTER synthesis
- Product Name:ADIPIC SEMIALDEHYDE METHYL ESTER
- CAS Number:6654-36-0
- Molecular formula:C7H12O3
- Molecular Weight:144.17
![6-HYDROXYHEXANOIC ACID METHYL ESTER](/CAS/GIF/4547-43-7.gif)
4547-43-7
73 suppliers
$19.00/100mg
![ADIPIC SEMIALDEHYDE METHYL ESTER](/CAS/GIF/6654-36-0.gif)
6654-36-0
82 suppliers
$20.00/250mg
Yield: 100%
Reaction Conditions:
with pyridinium chlorochromate in dichloromethane at 20; for 2.5 h;
Steps:
2
PCC (2.65 g, 12.3 mmoles) was added to a solution of methyl 6-hydroxyhexanoate (4) (1.2 g, 8.19 mmoles) in CH2Cl2 (50 ml). The mixture was stirred at room temperature for 2.5 hours. After that time, the solvent was removed under reduced pressure. The residue was suspended in a 1:1 hexane/AcOEt mixture (30 ml) and filtered through silica gel to remove the remains of the reagent, obtaining (1.16 g, quantitative yield) methyl 5-formylpentanoate (5), which was used in the following step without purifying. 1H-NMR (200MHz, CDCl3). δ 9.71 (1H, m, H-6), 3.61 (3H, s, -OCH3), 2.39 (4H, m, H-2, H-5), 1.65 (4H, m, H-3, H-4).
References:
Consejo Superior de Investigaciones Cientificas EP2287146, 2011, A1 Location in patent:Page/Page column 16
![Monomethyl adipate](/CAS/GIF/627-91-8.gif)
627-91-8
287 suppliers
$7.00/10g
![ADIPIC SEMIALDEHYDE METHYL ESTER](/CAS/GIF/6654-36-0.gif)
6654-36-0
82 suppliers
$20.00/250mg
![METHYL ADIPOYL CHLORIDE](/CAS/GIF/35444-44-1.gif)
35444-44-1
69 suppliers
$16.00/1g
![ADIPIC SEMIALDEHYDE METHYL ESTER](/CAS/GIF/6654-36-0.gif)
6654-36-0
82 suppliers
$20.00/250mg
![METHYL 4-PENTENOATE](/CAS/GIF/818-57-5.gif)
818-57-5
40 suppliers
$98.00/1g-f
201230-82-2
1 suppliers
inquiry
![ADIPIC SEMIALDEHYDE METHYL ESTER](/CAS/GIF/6654-36-0.gif)
6654-36-0
82 suppliers
$20.00/250mg
![Acetic anhydride](/CAS/20180808/GIF/108-24-7.gif)
108-24-7
5 suppliers
$14.00/250ML
![Cyclohexene](/CAS/GIF/110-83-8.gif)
110-83-8
290 suppliers
$11.00/25g
![ADIPIC SEMIALDEHYDE METHYL ESTER](/CAS/GIF/6654-36-0.gif)
6654-36-0
82 suppliers
$20.00/250mg