Adrenosterone synthesis
- Product Name:Adrenosterone
- CAS Number:382-45-6
- Molecular formula:C19H24O3
- Molecular Weight:300.39
382-44-5
102 suppliers
$73.20/10mg
382-45-6
157 suppliers
$45.00/1mg
Yield:382-45-6 90%
Reaction Conditions:
with chromium(VI) oxide in water;acetic acid for 1.5 h;
Steps:
7a.2 Step 2:
A solution of chromium trioxide (0.364 g, 3.64mmol) in water (lmL) was added drop wise to a solution of compound [10] (1 g, 3.31mmol) in acetic acid (30ml). The reaction was stirred for 1.5 hr and quenched by the addition of methanol (30mL) while stirring for 0.5 hr. The mixture was concentrated by rotovap at 70°C, dissolved in ethyl acetate/methanol, washed with saturated sodium bicarbonate and brine, dried over sodium sulfate and concentrated to give compound [11] as an off white solid (0.9g) with 90% yield.MS (ESI) m z (M+H+) 301.
References:
SPHAERA PHARMA PVT. LTD.;DUGAR, Sundeep;MAHAJAN, Dinesh;SCHREINER, George, Frederick WO2016/13030, 2016, A2 Location in patent:Page/Page column 50; 51
50-23-7
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$21.00/1g
382-45-6
157 suppliers
$45.00/1mg
53-06-5
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$25.00/250mg
382-45-6
157 suppliers
$45.00/1mg
566-35-8
61 suppliers
$495.52/5MG
382-45-6
157 suppliers
$45.00/1mg