Amentoflavone synthesis
- Product Name:Amentoflavone
- CAS Number:1617-53-4
- Molecular formula:C30H18O10
- Molecular Weight:538.46
548-19-6
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1617-53-4
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Yield:-
Reaction Conditions:
with pyridine hydrochloride at 180;
Steps:
Treatment of isoginkgetin with a large excess of methyl iodide (5 equiv) under basic conditions furnished fully methylated compound 11 [cf. Scheme 2 (Fig. 6)] . The use of 3 equivalents of Mel produced a mixture of trialkylated products 9 and 10 which were easily separated by column chromatography. Reaction of isoginkgetin with pyridinium chloride allows ether cleavage and afforded the polyphenolic compound 12. Scheme 2 (cf. Figure 6):
References:
INSTITUT GUSTAVE ROUSSY;APCHER, Sébastien;PIERSON, Alison;BOULPICANTE, Mathilde;DOLOR, Renko, Zafiarisoa;ALAMI, Mouad;DARRIGRAND, Romain WO2018/189210, 2018, A1 Location in patent:Page/Page column 23-24
48236-96-0
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1617-53-4
240 suppliers
$25.00/1mg