![](/CAS/GIF/1254053-43-4.gif)
Gilteritinib synthesis
- Product Name:Gilteritinib
- CAS Number:1254053-43-4
- Molecular formula:C29H44N8O3
- Molecular Weight:552.71
Reference: Yue, Qinglei; Zhou, Zhiguo; Gao, Qiang; Zheng, Baofu. Preparation of Gilteritinib derivatives as inhibitors of FLT3-Axl. Assignee Shanghai Haoyuan Medchemexpress Co., Ltd., Peop. Rep. China. CN 106083821. (2016).
![4-Aminotetrahydropyran hydrochloride](/CAS/GIF/33024-60-1.gif)
33024-60-1
204 suppliers
$6.00/1g
![Gilteritinib](/CAS/GIF/1254053-43-4.gif)
1254053-43-4
147 suppliers
$25.00/1mg
Yield:-
Steps:
Multi-step reaction with 3 steps
1: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C
2: palladium diacetate; potassium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene / 1,4-dioxane / 90 °C
3: sodium hydroxide; dihydrogen peroxide / dimethyl sulfoxide; ethanol / 3 h / 20 °C
References:
Medchemexpress China Co., Ltd.;Yue, Qinglei;Zhou, Zhiguo;Gao, Qiang;Zheng, Baofu CN106083821, 2016, A