Benzamide, 4-bromo-2-fluoro-6-methyl- synthesis

Yield:1242156-51-9 87%

Reaction Conditions:

with ammonium hydroxide;1,1'-carbonyldiimidazole in tetrahydrofuran at 20;Inert atmosphere;

References:

Lou, Yan;Han, Xiaochun;Kuglstatter, Andreas;Kondru, Rama K.;Sweeney, Zachary K.;Soth, Michael;McIntosh, Joel;Litman, Renee;Suh, Judy;Kocer, Buelent;Davis, Dana;Park, Jaehyeon;Frauchiger, Sandra;Dewdney, Nolan;Zecic, Hasim;Taygerly, Joshua P.;Sarma, Keshab;Hong, Junbae;Hill, Ronald J.;Gabriel, Tobias;Goldstein, David M.;Owens, Timothy D. [Journal of Medicinal Chemistry,2015,vol. 58,# 1,p. 512 - 516]