BenzaMide, N-ethyl-3-nitro- synthesis
- Product Name:BenzaMide, N-ethyl-3-nitro-
- CAS Number:26819-11-4
- Molecular formula:C9H10N2O3
- Molecular Weight:194.19
75-04-7
381 suppliers
$10.00/20mg
121-90-4
5 suppliers
$24.00/25g
26819-11-4
21 suppliers
$45.00/100mg
Yield:-
Reaction Conditions:
in dichloromethane;
Steps:
18.A Step A
Step A N-Ethyl-3-nitrophenylcarboxamide Ice cold ethylamine (33 ml) was added dropwise from a dropping funnel to a stirred, cooled (0° C.) solution of 3-nitrobenzoyl chloride (10.0 g) in anhydrous dichloromethane (100 ml). After addition the cooling bath was removed and the reaction mixture was stirred at room temperature for 1 hour. The solution was washed with water (2*50 ml), dried (sodium sulphate) then evaporated to give a solid which was recrystallized from dichloromethane/n-hexane to give the title compound as a colourless crystalline solid (10.10 g). mp 122°-123° C. Rf 0.44 in ethyl acetate on silica plates. Found: C, 56.11; H, 5.23; N, 14.62. C9 H10 N2 O3 requires C, 55.67; H, 5.19; N, 14.43%.
References:
US5696110,1997,A
557-66-4
269 suppliers
$26.00/25g
121-90-4
5 suppliers
$24.00/25g
26819-11-4
21 suppliers
$45.00/100mg