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ChemicalBook CAS DataBase List Benzamide, N,N,3-trimethyl- (9CI)

Benzamide, N,N,3-trimethyl- (9CI) synthesis

8synthesis methods
-

Yield:6935-65-5 92 %

Reaction Conditions:

Stage #1: ortho-methylbenzoic acidwith thionyl chloride in dichloromethane at 0 - 25;Inert atmosphere;
Stage #2: dimethyl amine in dichloromethane;water at 0 - 25;Inert atmosphere;

References:

Marcos-Atanes, Daniel;Vidal, Cristian;Navo, Claudio D.;Peccati, Francesca;Jiménez-Osés, Gonzalo;Mascare?as, José L. [Angewandte Chemie - International Edition,2023,vol. 62,# 18,art. no. E202214510][Angew. Chem.,2023,vol. 135,# 18] Location in patent:supporting information

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