Benzene, 2-methyl-1-nitro-4-propoxy- synthesis
1synthesis methods
- Product Name:Benzene, 2-methyl-1-nitro-4-propoxy-
- CAS Number:52177-07-8
- Molecular formula:C10H13NO3
- Molecular Weight:195.22
Yield:52177-07-8 99%
Reaction Conditions:
Stage #1: 3-methyl-4-nitrophenolwith potassium carbonate in butanone; for 0.0833333 h;Inert atmosphere;Reflux;
Stage #2: propyl bromide in butanone; for 18 h;Inert atmosphere;
References:
Trabbic, Christopher J.;Overmeyer, Jean H.;Alexander, Evan M.;Crissman, Emily J.;Kvale, Heather M.;Smith, Marcie A.;Erhardt, Paul W.;Maltese, William A. [Journal of Medicinal Chemistry,2015,vol. 58,# 5,p. 2489 - 2512]