Benzeneacetyl chloride, 4-nitro-alpha-oxo- (9CI) synthesis
- Product Name:Benzeneacetyl chloride, 4-nitro-alpha-oxo- (9CI)
- CAS Number:105248-77-9
- Molecular formula:C8H4ClNO4
- Molecular Weight:213.57
14922-36-2
76 suppliers
$53.00/250mg
105248-77-9
2 suppliers
inquiry
Yield:105248-77-9 95%
Reaction Conditions:
with oxalyl dichloride in dichloromethane;N,N-dimethyl-formamide at 45; for 1.03333 h;Inert atmosphere;
Steps:
3.2.2. 2-(4-nitrophenyl)-2-oxoacetyl chloride (6)
4-nitrophenylglyoxylic acid (5) was obtained as a pale yellowishbrown solid by the previously reported methods [27]. (Scheme 1) Then,4-nitrophenylglyoxylic acid (39 mg, 0.2 mmol), oxaloyl chloride (53 μL,0.6 mmol) and 3 mL dichloromethane were mixed and stirred for 2 min,and two drops of N, N-dimethylformamide (DMF) were added. Underthe protection of nitrogen, the temperature rose to 45 °C. After 1 h, the mixture was cooled to room temperature. Then, the solvent and excessoxaloyl chloride were evaporated, affording the product (40.4 mg,95%) as a light yellow transparent oil liquid.
References:
Huang, Xin;Li, Zhipeng;Liu, Zixin;Zeng, Chengchu;Hu, Liming [Dyes and Pigments,2019,vol. 165,p. 518 - 523]
57699-27-1
17 suppliers
inquiry
105248-77-9
2 suppliers
inquiry
100-19-6
304 suppliers
$5.00/5g
105248-77-9
2 suppliers
inquiry