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Benzeneacetyl chloride, alpha-oxo- (9CI) synthesis

12synthesis methods
1603-79-8 Synthesis
Ethyl benzoylformate

1603-79-8
202 suppliers
$7.00/5g

Benzeneacetyl chloride, alpha-oxo- (9CI)

25726-04-9
9 suppliers
inquiry

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Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium hydroxide; water / 2 h / 20 °C
2: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 20 °C / Inert atmosphere

References:

Weng, Jian-Quan;Deng, Qiao-Man;Wu, Liang;Xu, Kai;Wu, Hao;Liu, Ren-Rong;Gao, Jian-Rong;Jia, Yi-Xia [Organic Letters,2014,vol. 16,# 3,p. 776 - 779]