Benzenepropanoic acid, 3-hydroxy-.alpha.-oxo- synthesis
- Product Name:Benzenepropanoic acid, 3-hydroxy-.alpha.-oxo-
- CAS Number:4607-41-4
- Molecular formula:C9H8O4
- Molecular Weight:180.1574
Yield:4607-41-4 36%
Reaction Conditions:
Stage #1: meta-hydroxybenzaldehyde;N-acetylglycinewith sodium acetate;acetic anhydride at 120; for 5 h;
Stage #2: with hydrogenchloride in acetic anhydride at 100; for 4 h;
References:
Bourgault, Jean Paul;Maddirala, Amarendar Reddy;Andreana, Peter R. [Organic and Biomolecular Chemistry,2014,vol. 12,# 41,p. 8125 - 8127] Location in patent:supporting information
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