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ChemicalBook CAS DataBase List Benzenepropanoic acid, 3-hydroxy-.alpha.-oxo-
4607-41-4

Benzenepropanoic acid, 3-hydroxy-.alpha.-oxo- synthesis

3synthesis methods
-

Yield:4607-41-4 36%

Reaction Conditions:

Stage #1: meta-hydroxybenzaldehyde;N-acetylglycinewith sodium acetate;acetic anhydride at 120; for 5 h;
Stage #2: with hydrogenchloride in acetic anhydride at 100; for 4 h;

References:

Bourgault, Jean Paul;Maddirala, Amarendar Reddy;Andreana, Peter R. [Organic and Biomolecular Chemistry,2014,vol. 12,# 41,p. 8125 - 8127] Location in patent:supporting information