benzo[4,5]thieno[2,3-d]pyriMidin-4-ol synthesis

6synthesis methods

Product Name:benzo[4,5]thieno[2,3-d]pyriMidin-4-ol
CAS Number:18774-49-7
Molecular formula:C10H6N2OS
Molecular Weight:202.23

ETHYL-2-AMINO-BENZO(B)THIOPHENE-3-CARBOXYLATE

7311-95-7
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$89.00/100mg

60100-09-6
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Yield:18774-49-7 72%

Reaction Conditions:

at 100; for 3 h;

Steps:

5

Preparation of Benzo[4.5]thieno[2,3-d]pyrimidin-4-ol (X); ix x; The solution of 10 millimol IX in 15 milliliter milliliter formamide was stirred at 100⁰C for 3 hours then cooled down to room temperature. The reaction mixture was poured onto crushed ice with continuous stirring then collected by filtration. The product was washed with water and n-hexane, then dried.Yield: 72 %

References:

WO2009/104026,2009,A1 Location in patent:Page/Page column 19

7311-95-7
71 suppliers
$89.00/100mg

18774-49-7
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References

5,6,7,8-TETRAHYDRO-[1]-BENZOTHIENO[2,3-D]PYRIMIDIN-4(1H)-ONE

14346-24-8
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$45.00/10mg

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References

108-94-1 Synthesis

108-94-1
527 suppliers
$12.00/50g

18774-49-7
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References

4506-71-2 Synthesis

ETHYL 2-AMINO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CARBOXYLATE

4506-71-2
200 suppliers
$6.00/1g

18774-49-7
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References