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Benzoic acid, 2-(carboxymethoxy)-3-methyl- synthesis

5synthesis methods
Benzoic acid, 2-(2-ethoxy-2-oxoethoxy)-3-methyl-, methyl ester

1616110-77-0
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Benzoic acid, 2-(carboxymethoxy)-3-methyl-

60770-15-2
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Yield:60770-15-2 87%

Reaction Conditions:

with potassium hydroxide in methanol;water;Reflux;

References:

Velagapudi, Uday Kiran;Langelier, Marie-France;Delgado-Martin, Cristina;Diolaiti, Morgan E.;Bakker, Sietske;Ashworth, Alan;Patel, Bhargav A.;Shao, Xuwei;Pascal, John M.;Talele, Tanaji T. [Journal of Medicinal Chemistry,2019,vol. 62,# 11,p. 5330 - 5357] Location in patent:supporting information