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ChemicalBook CAS DataBase List Benzoic acid, 4-cyano-2-fluoro-, ethyl ester (9CI)

Benzoic acid, 4-cyano-2-fluoro-, ethyl ester (9CI) synthesis

2synthesis methods
-

Yield:220389-15-1 93%

Reaction Conditions:

with benzotriazol-1-ol;1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;N-ethyl-N,N-diisopropylamine in N,N-dimethyl-formamide at 20; for 14 h;

References:

Lund, Birgitte W.;Piu, Fabrice;Gauthier, Natalie K.;Eeg, Anne;Currier, Erika;Sherbukhin, Vladimir;Brann, Mark R.;Hacksell, Uli;Olsson, Roger [Journal of Medicinal Chemistry,2005,vol. 48,# 24,p. 7517 - 7519]