![](/CAS/GIF/21598-08-3.gif)
BENZOOXAZOLE-2-CARBOXYLIC ACID synthesis
- Product Name:BENZOOXAZOLE-2-CARBOXYLIC ACID
- CAS Number:21598-08-3
- Molecular formula:C8H5NO3
- Molecular Weight:163.13
![Benzoxazole](/CAS/GIF/273-53-0.gif)
273-53-0
196 suppliers
$10.00/5g
![Carbon dioxide](/CAS/GIF/124-38-9.gif)
124-38-9
122 suppliers
$175.00/23402
![BENZOOXAZOLE-2-CARBOXYLIC ACID](/CAS/GIF/21598-08-3.gif)
21598-08-3
69 suppliers
$50.00/50 mg
Yield: 94%
Reaction Conditions:
Stage #1:carbon dioxide with AuOH(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene);potassium hydroxide in tetrahydrofuran at 20; under 1125.11 Torr; for 0.25 h;
Stage #2:benzoxazole in tetrahydrofuran at 20; under 1125.11 Torr; for 12 h;
Stage #3: with hydrogenchloride in tetrahydrofuran;waterregioselective reaction;
References:
Boogaerts, Ine I. F.;Nolan, Steven P. [Journal of the American Chemical Society,2010,vol. 132,# 26,p. 8858 - 8859] Location in patent:supporting information; experimental part
![2H-1,4-Benzoxazin-3-amine, 2-imino-](/CAS/20210305/GIF/90004-00-5.gif)
90004-00-5
0 suppliers
inquiry
![BENZOOXAZOLE-2-CARBOXYLIC ACID](/CAS/GIF/21598-08-3.gif)
21598-08-3
69 suppliers
$50.00/50 mg
![2-Methylbenzoxazole](/CAS/GIF/1033202-12-8.gif)
95-21-6
151 suppliers
$8.00/5g
![BENZOOXAZOLE-2-CARBOXYLIC ACID](/CAS/GIF/21598-08-3.gif)
21598-08-3
69 suppliers
$50.00/50 mg