BENZOTRIAZOLE-1-CARBONYL CHLORIDE TECH. synthesis
2synthesis methods
- Product Name:BENZOTRIAZOLE-1-CARBONYL CHLORIDE TECH.
- CAS Number:65095-13-8
- Molecular formula:C7H4ClN3O
- Molecular Weight:181.58
Yield:-
Reaction Conditions:
in tetrahydrofuran;toluene at 0 - 20; for 2 h;
Steps:
B.a Method Ba)
Preparation of a benzotriazole-1-carbonyl chloride Solution
A solution of benzotriazole (6 g, 50.4 mmol) in THF (100 ml) is added dropwise to a phosgene solution (20% in toluene; 90 ml; 182 mmol) while cooling in ice.The ice bath is removed and the solution is then stirred at RT for a further 2 h.The solvent is distilled out and the residue is taken up in THF to give a total volume of 25 ml.
References:
US2004/127484,2004,A1 Location in patent:Page/Page column 13
