![](/CAS/GIF/101625-10-9.gif)
BENZYL (4-BROMOBUTYL)CARBAMATE synthesis
- Product Name:BENZYL (4-BROMOBUTYL)CARBAMATE
- CAS Number:101625-10-9
- Molecular formula:C12H16BrNO2
- Molecular Weight:286.16
![Carbon tetrabromide](/CAS/GIF/558-13-4.gif)
558-13-4
253 suppliers
$10.00/1g
![4-(Z-AMINO)-1-BUTANOL](/CAS/GIF/17996-13-3.gif)
17996-13-3
65 suppliers
$23.00/250mg
![BENZYL (4-BROMOBUTYL)CARBAMATE](/CAS/GIF/101625-10-9.gif)
101625-10-9
8 suppliers
inquiry
Yield:101625-10-9 99.5%
Reaction Conditions:
with triphenylphosphine in dichloromethane;
Steps:
22.b 6-Amino-2-((2-methyl-1-(3-phenylpropanoylamino)propyl)hydroxyphosphinoyl)methylhexanoic acid
(b) The 4-benzyloxycarbonylamino-1-butanol (8.15 g) obtained in the above step (a) and carbon tetrabromide (15.12 g) were dissolved in methylene chloride (130.4 ml) and cooled with water. The mixture was added with triphenylphosphine (14.4 g) and returned to room temperature, and then stirred for 4 hours. The reaction system was concentrated under reduced pressure without any treatment, and the residue was purified by silica gel column chromatography (400 g, hexane:ethyl acetate=5:2) to obtain 1-benzyloxycarbonylamino-4-bromobutane (10.4 g, 99.5%). 1H-NMR(CDCl3): δ1.58-1.72(2H,m), 1.84-1.94(2H,m), 3.18-3.28(2H,dd), 3.42(2H,dd), 4.80(1H,s), 5.10(2H,s), 7.29-7.39(5H,m). EIMS(m/z): 286(M+).
References:
US6576627,2003,B1
![4-(Z-AMINO)-1-BUTANOL](/CAS/GIF/17996-13-3.gif)
17996-13-3
65 suppliers
$23.00/250mg
![BENZYL (4-BROMOBUTYL)CARBAMATE](/CAS/GIF/101625-10-9.gif)
101625-10-9
8 suppliers
inquiry
![1-ButanaMine, 4-broMo-, hydrobroMide](/CAS/GIF/24566-81-2.gif)
24566-81-2
93 suppliers
$9.00/250mg
![Benzyl chloroformate](/CAS/GIF/501-53-1.gif)
501-53-1
393 suppliers
$10.00/1g
![BENZYL (4-BROMOBUTYL)CARBAMATE](/CAS/GIF/101625-10-9.gif)
101625-10-9
8 suppliers
inquiry
![N-Bromosuccinimide](/CAS/GIF/128-08-5.gif)
128-08-5
829 suppliers
$5.00/5G
![4-(Z-AMINO)-1-BUTANOL](/CAS/GIF/17996-13-3.gif)
17996-13-3
65 suppliers
$23.00/250mg
![BENZYL (4-BROMOBUTYL)CARBAMATE](/CAS/GIF/101625-10-9.gif)
101625-10-9
8 suppliers
inquiry
![Benzyl chloroformate](/CAS/GIF/501-53-1.gif)
501-53-1
393 suppliers
$10.00/1g
![BENZYL (4-BROMOBUTYL)CARBAMATE](/CAS/GIF/101625-10-9.gif)
101625-10-9
8 suppliers
inquiry