Benzyl-PEG7-amino synthesis

Yield:868594-43-8 97%

Reaction Conditions:

Stage #1: 1-azido-20-(phenylmethyloxy)-3,6,9,12,15,18-hexaoxaeicosanewith triphenylphosphine in tetrahydrofuran at 20; for 3 h;Staudinger reaction;
Stage #2: with water in tetrahydrofuran at 20; for 48 h;

References:

Pilkington-Miksa, Michael A.;Sarkar, Supti;Writer, Michele J.;Barker, Susie E.;Shamlou, Parviz Ayazi;Hart, Stephen L.;Hailes, Helen C.;Tabor, Alethea B. [European Journal of Organic Chemistry,2008,# 17,p. 2900 - 2914] Location in patent:experimental part