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(BIPHENYL-2-YLOXY)-ACETIC ACID synthesis

11synthesis methods
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Yield:5348-75-4 89%

Reaction Conditions:

Stage #1: 2-Phenylphenolwith sodium hydride in tetrahydrofuran;mineral oil at 20; for 0.75 h;Inert atmosphere;
Stage #2: bromoacetic acid in tetrahydrofuran;mineral oil at 20;Inert atmosphere;

References:

Pinter, Aron;Klussmann, Martin [Advanced Synthesis and Catalysis,2012,vol. 354,# 4,p. 701 - 711] Location in patent:supporting information; experimental part