bis(2-fluorophenyl)methanol synthesis

6synthesis methods

Product Name:bis(2-fluorophenyl)methanol
CAS Number:261925-13-7
Molecular formula:C13H10F2O
Molecular Weight:220.22

1072-85-1 Synthesis

1072-85-1
452 suppliers
$5.00/10g

29786-93-4 Synthesis

29786-93-4
0 suppliers
inquiry

109-94-4 Synthesis

109-94-4
463 suppliers
$10.00/10g

623-93-8
77 suppliers
$35.81/25g

261925-13-7
5 suppliers
inquiry

Yield:261925-13-7 89%

Reaction Conditions:

Stage #1: o-fluorobromobenzene;n-butyllithium in tetrahydrofuran;hexane at -78 - -30; for 1.66667 h;Inert atmosphere;
Stage #2: formic acid ethyl ester in tetrahydrofuran;hexane at -78 - -30;Inert atmosphere;
Stage #3: with water;ammonium chloride in tetrahydrofuran;hexane;

References:

Bunce, Richard A.;Grant, Matthew T. [Organic Preparations and Procedures International,2011,vol. 43,# 3,p. 265 - 275] Location in patent:experimental part

1072-85-1 Synthesis

1072-85-1
452 suppliers
$5.00/10g

446-52-6 Synthesis