Bis(o-tolyl) sulfone synthesis

6synthesis methods

Product Name:Bis(o-tolyl) sulfone
CAS Number:5097-12-1
Molecular formula:
Molecular Weight:0

15898-37-0
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5097-12-1
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Yield:5097-12-1 76%

Reaction Conditions:

with copper diacetate in acetonitrile at 60; for 3 h;

Steps:

Typical procedure for the products

General procedure: A mixture of the sodium arylsulfinate (1 mmol), Cu(OAc)2 (0.5 mmol)and CH3CN (1 mL) was stirred at 60 °C in air for 3 h. After this, themixture was cooled to room temperature and filtered through a filterpaper. The organic phases were evaporated under reduced pressure andthe residue was subjected to flash column chromatography (silica gel,ethyl acetate/petroleum ether = 1/10) to obtain the desired product.All products are known compounds and were characterised by 1HNMR, 13C NMR and HRMS.

References:

Peng, Yao [Journal of Chemical Research,2014,vol. 38,# 5,p. 265 - 268]