![](/CAS/GIF/144072-29-7.gif)
BOC-4-AMINOBENZYLALCOHOL synthesis
- Product Name:BOC-4-AMINOBENZYLALCOHOL
- CAS Number:144072-29-7
- Molecular formula:C12H17NO3
- Molecular Weight:223.27
![Di-tert-butyl dicarbonate](/CAS/GIF/24424-99-5.gif)
24424-99-5
821 suppliers
$13.50/25G
![4-Aminobenzyl alcohol](/CAS/GIF/623-04-1.gif)
623-04-1
348 suppliers
$6.00/1g
![BOC-4-AMINOBENZYLALCOHOL](/CAS/GIF/144072-29-7.gif)
144072-29-7
86 suppliers
$8.00/250mg
Yield: 100%
Reaction Conditions:
with N-ethyl-N,N-diisopropylamine in tetrahydrofuranHeating / reflux;
Steps:
10
To a solution of p-amino-benzylalcohol (1 g, 8.12 mmol, 1 eq) in 80 mL of anhydrous THF were added DIEA (1.4 mL, 8.12 mmol, 1 eq) and BoC2O (1.9 mL, 8.12 mmol, 1 eq). The mixture was heated to reflux overnight, then cooled down and evaporated under vacuum. The residue was dissolved in EtOAc. The organic layer was washed with a 0.1 N HCl solution, dried over MgSO4, filtered and evaporated under vacuum. The crude product was purified by
References:
ENZON PHARMACEUTICALS, INC. WO2008/34124, 2008, A2 Location in patent:Page/Page column 72-73
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144072-30-0
95 suppliers
$22.00/250mg
![BOC-4-AMINOBENZYLALCOHOL](/CAS/GIF/144072-29-7.gif)
144072-29-7
86 suppliers
$8.00/250mg
![Carbonic acid, bis(1,1-dimethylethyl) ester](/CAS/20180601/GIF/34619-03-9.gif)
34619-03-9
27 suppliers
inquiry
![4-Aminobenzyl alcohol](/CAS/GIF/623-04-1.gif)
623-04-1
348 suppliers
$6.00/1g
![BOC-4-AMINOBENZYLALCOHOL](/CAS/GIF/144072-29-7.gif)
144072-29-7
86 suppliers
$8.00/250mg
![ETHYL 4-(TERT-BUTOXYCARBONYLAMINO)BENZOATE](/CAS/GIF/110969-44-3.gif)
110969-44-3
17 suppliers
$333.00/5g
![BOC-4-AMINOBENZYLALCOHOL](/CAS/GIF/144072-29-7.gif)
144072-29-7
86 suppliers
$8.00/250mg
![Di-tert-butyl dicarbonate](/CAS/GIF/24424-99-5.gif)
24424-99-5
821 suppliers
$13.50/25G
![4-Aminobenzoic acid](/CAS/GIF/150-13-0.gif)
150-13-0
884 suppliers
$5.00/25g
![BOC-4-AMINOBENZYLALCOHOL](/CAS/GIF/144072-29-7.gif)
144072-29-7
86 suppliers
$8.00/250mg