BUTTPARK 99\18-37 synthesis

4synthesis methods

Product Name:BUTTPARK 99\18-37
CAS Number:128564-57-8
Molecular formula:C6H3Cl2F3N2O
Molecular Weight:247

5-CHLORO-1-METHYL-3-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID

128455-63-0
71 suppliers
$29.00/250mg

$BUTTPARK 99\18-37$

128564-57-8
17 suppliers
inquiry

Yield:128564-57-8 87.5%

Reaction Conditions:

with thionyl chlorideReflux;

Steps:

1.4 (4) Preparation of 1-methyl-3-trifluoromethyl-5-chloro-4-pyrazoloyl chloride intermediate:

To a 150 mL three-necked flask, 0.1 mol of 1-methyl-3-trifluoromethyl-5-chloro-4-pyrazoleacetic acid was added,10 mL of re-distilled SOCl2 was slowly added dropwise to the reaction system, refluxed, and neutralized with Ph test paper, And the SOCl2 solvent was distilled off under reduced pressure. Yield: 87.5%

References:

CN103951663,2016,B Location in patent:Paragraph 0091; 0098; 0099

128455-62-9 Synthesis