C.I. 564100 synthesis
- Product Name:C.I. 564100
- CAS Number:6925-69-5
- Molecular formula:C18H10N2O
- Molecular Weight:270.28
Yield:6925-69-5 99.2%
Reaction Conditions:
with SA in 1-methyl-pyrrolidin-2-one at 50 - 125;Large scale;Concentration;
Steps:
1.a-1.c; 1-5; 1-2
(a) Add 600 kilograms of NMP to the reaction vessel in turn, raise the temperature to 50, put in 240 kilograms of 1,8-diaminonaphthalene, 230 kilograms of phthalic anhydride, and 1.5 kilograms of SA cat, stir evenly and continue to heat up to 115-125 for reaction Hours, use HPLC to determine the end of the reaction; (b) Then the temperature is lowered to 20°C, stirred for 2 hours, and filtered with suction to obtain a filter cake and filtrate; (c) Wash the filter cake with 500 kg of hot water, collect the washing liquid and filtrate, and distill to recover the solvent; then wash the filter cake with 90-100°C hot water to neutrality, dry, crush, and pack 407 kg of solvent orange 60 products were obtained; the yield was 99.2%. △E is 0.833, △C is 0.705, and the pressure value is 0.15.
References:
CN112592603, 2021, A Location in patent:Paragraph 0021; 0023-0039
