ChemicalBook CAS DataBase List CBZ-TAURYLSULFONYL CHLORIDE

CBZ-TAURYLSULFONYL CHLORIDE synthesis

6synthesis methods

Product Name:CBZ-TAURYLSULFONYL CHLORIDE
CAS Number:52530-50-4
Molecular formula:C10H12ClNO4S
Molecular Weight:277.72

136027-16-2 Synthesis

136027-16-2
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52530-50-4
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Yield:52530-50-4 91%

Reaction Conditions:

with thionyl chloride in N,N-dimethyl-formamide; for 3 h;Reflux;

Steps:

1.b

b. Synthesis of 2-benzyloxyformamidoethylsulfonyl chloride: [Show Image] In a reaction flask, 20.0g of amino-Cbz protected sodium taurate, SOCl₂ (30ml) and DMF 1 ml were added. The mixture was reacted under refluxing for 3h, cooled to room temperature, filtrated, and distilled under a reduced pressure to remove the solvent to obtain 17.9g of oily product, yield 91%.

References:

EP2484678,2012,A1 Location in patent:Page/Page column 14