![](/CAS/GIF/751468-47-0.gif)
CHEMBRDG-BB 4010847 synthesis
- Product Name:CHEMBRDG-BB 4010847
- CAS Number:751468-47-0
- Molecular formula:C11H15FN2
- Molecular Weight:194.25
![1H-1,4-Diazepine-1-carboxylic acid, 4-(4-fluorophenyl)hexahydro-, 1,1-dimethylethyl ester](/CAS/20210305/GIF/263409-95-6.gif)
263409-95-6
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![CHEMBRDG-BB 4010847](/CAS/GIF/751468-47-0.gif)
751468-47-0
15 suppliers
$130.00/250mg
Yield:751468-47-0 88%
Reaction Conditions:
with trifluoroacetic acid in dichloromethane at 20; for 0.333333 h;
Steps:
General procedure C for Boc deprotection of piperazine analogs
General procedure: To a solution of N-Boc piperazine analog (0.44 mmol, 1 eq.) in DCM (3 mL) was added TFA (3 mL). The mixture was stirred at rt for 20 min, then quenched with a NaH CO3 saturated solution. The aqueous phase was extracted with DCM. The organic layer was dried over anhydrous MgSO4 , concentrated under reduced pressure to afford the desired compound without further purification.
References:
WO2022/195102,2022,A1 Location in patent:Page/Page column 59; 70-71
![1-Boc-hexahydro-1,4-diazepine](/CAS/GIF/112275-50-0.gif)
112275-50-0
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![CHEMBRDG-BB 4010847](/CAS/GIF/751468-47-0.gif)
751468-47-0
15 suppliers
$130.00/250mg
![1-Boc-hexahydro-1,4-diazepine](/CAS/GIF/112275-50-0.gif)
112275-50-0
243 suppliers
$9.00/1g
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460-00-4
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![CHEMBRDG-BB 4010847](/CAS/GIF/751468-47-0.gif)
751468-47-0
15 suppliers
$130.00/250mg