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CHEMBRDG-BB 4015724 synthesis

5synthesis methods
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Yield:76955-91-4 1.05 g

Reaction Conditions:

Stage #1: 1-aminoguanidine hydrochloride;hydrocinnamic acid chloride at 145 - 150; for 0.166667 h;
Stage #2: with sodium hydroxide in water; for 0.5 h;Reflux;

References:

Palysaeva, Nadezhda V.;Kumpan, Katerina P.;Struchkova, Marina I.;Dalinger, Igor L.;Kormanov, Aleksandr V.;Aleksandrova, Nataly S.;Chernyshev, Victor M.;Pyreu, Dmitrii F.;Suponitsky, Kyrill Yu.;Sheremetev, Aleksei B. [Organic Letters,2014,vol. 16,# 2,p. 406 - 409] Location in patent:supporting information

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