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CHEMBRDG-BB 5636113 synthesis

1synthesis methods
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Yield:915920-86-4 86%

Reaction Conditions:

Stage #1: 1,2,4-Triazole;1-Adamantanaminewith ammonium nitrate;sulfuric acid in water at 20; for 24 h;
Stage #2: with ammonia in water; pH=8 - 9;

References:

Zarubaev, Vladimir V.;Golod, Efim L.;Anfimov, Pavel M.;Shtro, Anna A.;Saraev, Victor V.;Gavrilov, Alexey S.;Logvinov, Alexander V.;Kiselev, Oleg I. [Bioorganic and Medicinal Chemistry,2010,vol. 18,# 2,p. 839 - 848] Location in patent:experimental part