CINNAMONITRILEE synthesis

5synthesis methods

Product Name:CINNAMONITRILEE
CAS Number:7520-75-4
Molecular formula:
Molecular Weight:0

7721-62-2
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$45.00/25mg

124-41-4 Synthesis

124-41-4
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107-13-1 Synthesis

107-13-1
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$17.00/25ML

7520-75-4
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Yield:7520-75-4 92%

Reaction Conditions:

in methanol at 50;

Steps:

2.5 (5) Synthesis of Compound V.

9 g of compound IV and 10.8 g of sodium methoxide were dissolved in 150 ml of methanol,Slowly add 8.1ml acrylonitrile, after the addition was warmed to 50 ° C,TLC monitoring of the reaction process; After the reaction was placed in an ice-water bath for about 1 hour,A pale yellow solid precipitation, suction filtration,After cold methanol and ice water washing several times to get white needle crystal,Drying in vacuo at 40 ° C gave 11.5 g of compound V in a molar yield of 92%.

References:

CN107311938,2017,A Location in patent:Paragraph 0052; 0053

494-99-5 Synthesis