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ChemicalBook CAS DataBase List CKD-516 (hydrochloride)

CKD-516 (hydrochloride) synthesis

1synthesis methods
CKD-516

1188371-47-2
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CKD-516 (hydrochloride)

1240321-53-2
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Yield:1240321-53-2 76%

Reaction Conditions:

with hydrogenchloride in 1,4-dioxane;methanol;water at 20; for 0.333333 h;

References:

Lee, Jaekwang;Kim, Soo Jin;Choi, Hojin;Kim, Young Hoon;Lim, In Taek;Yang, Hyun-Mo;Lee, Chang Sik;Kang, Hee Ryong;Ahn, Soon Kil;Moon, Seung Kee;Kim, Dal-Hyun;Lee, Sungsook;Choi, Nam Song;Lee, Kyung Joo [Journal of Medicinal Chemistry,2010,vol. 53,# 17,p. 6337 - 6354] Location in patent:experimental part