CLAMIKALANT synthesis

4synthesis methods

Product Name:CLAMIKALANT
CAS Number:158751-64-5
Molecular formula:C19H22ClN3O5S2
Molecular Weight:471.98

556-61-6
175 suppliers
$27.50/5g

N-[2-[3-(AMINOSULFONYL)-4-METHOXYPHENYL]ETHYL]-5-CHLORO-2-METHOXY-BENZAMIDE

158751-78-1
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158751-64-5
13 suppliers
$294.00/0.05G

Yield:158751-64-5 96%

Reaction Conditions:

with hydrogenchloride in N-methyl-acetamide;

Steps:

2 1-(5-(2-(5-Chloro-2-methoxybenzamido)ethyl)-2-methoxyphenylsulfonyl)-3-methylthiourea

Example 2 1-(5-(2-(5-Chloro-2-methoxybenzamido)ethyl)-2-methoxyphenylsulfonyl)-3-methylthiourea 400 mg of 5-(2-(5-chloro-2-methoxybenzamido)ethyl)-2-methoxybenzenesulfonamide were dissolved in 5 ml of absolute dimethylformamide and 42 mg of 60% sodium hydride were added. The mixture was stirred at room temperature for 30 min. 1.2 ml of a 1M solution of methyl isothiocyanate in dimethylformamide were then added dropwise and the mixture was heated at 80° C. for 1.5 h. After it had been cooled down, the reaction mixture was added dropwise to 50 ml of 1N hydrochloric acid. The precipitated product was filtered off with suction and dried. Yield 96%. Melting point 190-193° C.

References:

US2003/83385,2003,A1

55-81-2 Synthesis

55-81-2
245 suppliers
$39.96/5g

158751-64-5
13 suppliers
$294.00/0.05G

References

29568-33-0
46 suppliers
$143.84/250MG

158751-64-5
13 suppliers
$294.00/0.05G

References

Benzamide, 5-chloro-2-methoxy-N-[2-(4-methoxyphenyl)ethyl]-

158751-77-0
5 suppliers
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158751-64-5
13 suppliers
$294.00/0.05G

References

CLAMIKALANT Related Search:

5-CHLORO-2-METHOXY-N-(2-PHENYLETHYL)BENZAMIDE