ChemicalBook CAS DataBase List CLOPROSTENOL LACTONE DIOL

CLOPROSTENOL LACTONE DIOL synthesis

7synthesis methods

Product Name:CLOPROSTENOL LACTONE DIOL
CAS Number:53906-54-0
Molecular formula:C17H19ClO5
Molecular Weight:338.78

54324-79-7 Synthesis

[1,1'-Biphenyl]-4-carboxylic acid [3aR-[3aa,4a(E),5b,6aa]]-4-[4-(3-chlorophenoxy)-3-oxo-1-butenyl]hexahydro-2-oxo-2H-cyclopenta[b]furan-5-yl ester

54324-79-7
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53906-54-0
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: lithium triethylborohydride / tetrahydrofuran / 0.5 h
2: potassium carbonate / methanol; tetrahydrofuran / 2.5 h

References:

Schaaf, Thomas K.;Bindra, Jasjit S.;Eggler, James F.;Plattner, Jacob J.;Nelson, A. James;et al. [Journal of Medicinal Chemistry,1981,vol. 24,# 11,p. 1353 - 1359]

CLOPROSTENOL LACTONE DIOL Related Search:

(+)-(3AR,4R,5R,6AS)-HEXAHYDRO-5-HYDROXY-4-[(1E,3R)-3-HYDROXY-4-(3-TRIFLUOROMETHYL)PHENOXY-1-BUTENYL]-2H-CYCLOPENTA[B]FURAN-2-ONE 5-(benzoyloxy)-3,3a,4,5,6,6a-hexahydro-4-(3-oxo-1-octenyl)-2H-cyclopenta(b)furan-2-one [1,1'-Biphenyl]-4-carboxylic acid [3aR-[3aa,4a(E),5b,6aa]]-4-[4-(3-chlorophenoxy)-3-oxo-1-butenyl]hexahydro-2-oxo-2H-cyclopenta[b]furan-5-yl ester