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α-Colubrine synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: (i) aq. NaNO2, H2SO4, (ii) aq. H2SO4, (heating)
2: methanol; CHCl3

References:

Rosenmund,P.;Franke,H. [Chemische Berichte,1964,vol. 97,p. 1677 - 1683]